From Syracuse and Buffalo and points west:
Take I-90 east to Exit 30 at Herkimer
Take Route 28 south to Cooperstown
From Albany and Boston and points east:
Take I-90 west to Exit 25A
Take I-88 west to Exit 24
Take Route 20 west to Route 80
Take Route 80 south to Cooperstown
From Binghamton and points south:
Take I-88 east to Exit 17
Take Route 28 north to Cooperstown
From Burlington, Vermont, and points north:
Take I-87 south to Albany
Take I-90 west to Exit 25A
Take I-88 west to Exit 24
Follow Route 7 to Route 20 west
Take Route 20 west to Route 80
Take Route 80 south to Cooperstown
From New York City:
Take I-87 north to I-90
Take I-90 west to Exit 25A
Take I-88 west to Exit 24
Follow Route 7 to Route 20 west
Take Route 20 west to Route 80
Take Route 80 south to Cooperstown