A Derek Nicholson two-run home run gave the Detroit Tigers a walk-off victory against the defending World Series champion Boston Red Sox in the 59th Hall of Fame Game on May 23, 2005, at Doubleday Field.
Nicholson, who was hitless before the home run, lined a 1-0 pitch over the center field wall to end the game.
Detroit struck early in the bottom of the first inning with four consecutive singles to take a quick 2-0 lead. Carlos Peña and Marcus Thames each recorded an RBI in the inning. Peña would go on to win the game’s Most Valuable Player Award.
Peña was also responsible for the Tigers’ third run of the game, hitting a solo shot over the left field fence in the third inning.
Brandon Inge bats for the Tigers during the 2005 Hall of Fame Game. (Milo Stewart Jr./National Baseball Hall of Fame and Museum)